5-Phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde(CAS: 881676-90-0)

5-Phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde is a crystalline solid with a high molecular weight. It has a low solubility in water but good solubility in organic solvents like dichloromethane. This compound is relatively stable under normal conditions but can react with nucleophiles, particularly under basic conditions. It is an important precursor in organic synthesis and pharmaceutical research.

5-Phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde is often synthesized via a multistep process involving the coupling of a phenyl group with a pyridin-3-ylsulfonyl group. Commonly, the synthesis involves the use of reagents like sulfonyl chloride and a condensing agent. The process requires careful control of temperature and reaction time to achieve high yield and selectivity.

5-Phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde is used in the pharmaceutical and chemical industries. It serves as a key intermediate in the synthesis of various drugs and functional materials. Its applications in semiconductors and organic electronics are also being explored for its unique electronic properties.

When handling 5-Phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde, it is crucial to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Ensure that the work is conducted in a well-ventilated area or a fume hood. Spills should be managed promptly with absorbent materials and cleaned with appropriate solvents. Always refer to the safety data sheet (SDS) for detailed handling instructions and emergency procedures.