5-[4-(Methylsulfonyl)phenyl]-6'-(trifluoromethyl)-3,3'-bipyridin-2-amine(CAS: 1314883-11-8)

The compound is a crystalline solid with a molecular weight of approximately 474.4 g/mol. It has low water solubility and is moderately soluble in organic solvents like DMSO and dimethylformamide. The compound is chemically stable but may react with strong bases. It can be dissolved in nonpolar solvents with difficulty.

The compound is synthesized via a multi-step process involving the reaction of 4-(methylsulfonyl)benzaldehyde with 2-aminobipyridine under controlled conditions. The synthesis typically requires the use of a Lewis acid catalyst and involves protecting groups for selective functionalization. The overall yield is around 70-75%.

The compound is primarily used in the pharmaceutical industry for its potential as a drug candidate due to its specific chemical structure. It also has applications in the development of sensors and as a precursor in the semiconductor industry for its electronic properties.

Proper Personal Protective Equipment (PPE) is essential, including gloves, goggles, and a lab coat. The compound should be handled in a fume hood to minimize inhalation risks. Spills should be handled according to standard safety protocols, using appropriate absorbents and disposing of waste according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.