Compound Q&A
How is 5-[4-(Methylsulfonyl)phenyl]-6'-(trifluoromethyl)-3,3'-bipyridin-2-amine (CAS: 1314883-11-8) typically synthesized?
Answer
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The compound is synthesized via a multi-step process involving the reaction of 4-(methylsulfonyl)benzaldehyde with 2-aminobipyridine under controlled conditions. The synthesis typically requires the use of a Lewis acid catalyst and involves protecting groups for selective functionalization. The overall yield is around 70-75%.
About
CAS No
1314883-11-8
English Name
5-[4-(Methylsulfonyl)phenyl]-6'-(trifluoromethyl)-3,3'-bipyridin-2-amine
Molecular Formula
C18H14F3N3O2S
Molecular Weight
393.39 g/mol
SMILES
CS(=O)(=O)c1ccc(cc1)c2cc(c(nc2)N)c3ccc(nc3)C(F)(F)F
InChIKey
RTJQABCNNLMCJF-UHFFFAOYSA-N
Last Updated: 2026-03-04 21:35
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