2'-O-(2-Methoxyethyl)-uridine(CAS: 223777-15-9)

2'-O-(2-Methoxyethyl)-uridine (CAS: 223777-15-9) is a white crystalline solid. Its molecular weight is approximately 317.24 g/mol. It is slightly soluble in water and ethanol. It is generally stable under normal conditions but should be stored in a dry environment to avoid hydrolysis. This compound reacts readily with strong acids and bases.

2'-O-(2-Methoxyethyl)-uridine (CAS: 223777-15-9) is typically synthesized through a nucleoside modification reaction. The reaction involves the methylation of the uridine at the 2'-position using 2-methoxyethyl chloride in the presence of a base, such as diisopropylethylamine (DIPEA), followed by purification steps to isolate the product. This method yields high purity with good selectivity.

2'-O-(2-Methoxyethyl)-uridine (CAS: 223777-15-9) is primarily used in the pharmaceutical industry for drug development, particularly in the field of antiviral and anticancer medications. It is also utilized in biosensor technologies and as a building block in some polymer synthesis processes.

When handling 2'-O-(2-Methoxyethyl)-uridine (CAS: 223777-15-9), it is important to wear appropriate personal protective equipment (PPE), such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to avoid inhalation. Spills should be carefully cleaned up using appropriate absorbent materials, and any waste should be disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.