(S)-1-N-Boc-4-N-Fmoc-piperazine-2-carboxylic acid(CAS: 1034574-30-5)

(S)-1-N-Boc-4-N-Fmoc-piperazine-2-carboxylic acid is a white crystalline solid with a molecular weight of approximately 535.56 g/mol. It has a pKa of about 6.5 and is soluble in common organic solvents like DMSO and DMF but less soluble in water. This compound is known for its reactivity in ester formation and amide bond formation, making it valuable in peptide synthesis.

(S)-1-N-Boc-4-N-Fmoc-piperazine-2-carboxylic acid is synthesized through a multi-step process, typically starting with piperazine-2-carboxylic acid. The key steps involve the substitution of the amine groups and the introduction of protecting groups. This synthesis often requires the use of reagents like tert-butyloxycarbonyl (Boc) and fluorenylmethyloxycarbonyl (Fmoc) groups, which are common in peptide chemistry.

(S)-1-N-Boc-4-N-Fmoc-piperazine-2-carboxylic acid finds applications in the pharmaceutical industry, where it serves as a building block for peptide synthesis. It is also utilized in the production of polymers and sensors, due to its unique chemical properties. In the semiconductor industry, it may be used in the development of specific components requiring high purity.

When handling (S)-1-N-Boc-4-N-Fmoc-piperazine-2-carboxylic acid, it is essential to wear appropriate personal protective equipment (PPE), such as gloves, goggles, and a lab coat. This compound should be stored in a cool, dry place and kept away from heat and open flames. In case of a spill, it should be cleaned up using appropriate methods, and the material safety data sheet (MSDS) should be consulted for specific guidelines.