3-Phenylpentanedioic acid(CAS: 4165-96-2)

3-Phenylpentanedioic acid is a white crystalline solid with a molecular weight of 174.23 g/mol. It is slightly soluble in water and alcohol. The acid is relatively stable but can undergo oxidation and dehydrogenation under certain conditions. It exhibits typical carboxylic acid reactivity, including esterification and acylation reactions.

3-Phenylpentanedioic acid is synthesized through a multi-step process, often starting with adipic acid and phenylacetic acid. Common methods involve the condensation of an appropriate dicarboxylic acid with a phenyl derivative, followed by acidification. Catalysts like sulfuric acid are used to promote the reaction, with a yield of around 70-80%.

3-Phenylpentanedioic acid finds applications in various industries. It is used in pharmaceuticals for the synthesis of certain drugs, in polymers for specialty plastic formulations, and in sensors for detecting specific chemicals. Its use in semiconductors is limited but explored for advanced material applications.

When handling 3-Phenylpentanedioic acid, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a cool, dry place away from direct sunlight and heat sources. Use fume hoods during handling to minimize inhalation risks. In case of a spill, neutralize with a base and dispose of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling instructions.