4-Chloro-6-methylpyrimidine(CAS: 3435-25-4)

4-Chloro-6-methylpyrimidine (CAS: 3435-25-4) is a white crystalline solid with a molecular weight of 152.59 g/mol. It is slightly soluble in water but more soluble in common organic solvents like ethanol and acetone. Chemically, it is relatively stable but can undergo nucleophilic substitution reactions. This compound is often used in medicinal and industrial applications due to its unique properties.

4-Chloro-6-methylpyrimidine is typically synthesized via direct chlorination of 6-methylpyrimidine in the presence of a catalyst such as thionyl chloride. The reaction involves the substitution of a hydrogen atom with a chlorine atom, yielding a high yield of the desired product with good selectivity.

4-Chloro-6-methylpyrimidine (CAS: 3435-25-4) is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various drugs, and in the polymer industry for the development of new materials. It also finds applications in the production of sensors and semiconductors for electronic devices.

When handling 4-Chloro-6-methylpyrimidine (CAS: 3435-25-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves and safety glasses. Work in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be handled using appropriate cleanup materials, and the area should be properly decontaminated. Refer to the Safety Data Sheet (SDS) for detailed instructions on handling and disposal.