2-Fluoro-D-phenylalanine(CAS: 97731-02-7)

2-Fluoro-D-phenylalanine is a crystalline compound with a molecular weight of approximately 185.14 g/mol. It has a low solubility in water but is more soluble in organic solvents like methanol and ethanol. Chemically, it is less reactive than the parent compound D-phenylalanine, making it suitable for specific synthetic applications. It exhibits good stability under anhydrous conditions but should be handled with care in the presence of moisture.

2-Fluoro-D-phenylalanine is typically synthesized through the fluorination of D-phenylalanine using Lewis acids such as phosphorus pentachloride (PCl5) or fluorine gas (F2). The reaction is carried out under anhydrous conditions to prevent side reactions. The yield is generally high, and the product is usually obtained in a crystalline form, facilitating easy purification.

2-Fluoro-D-phenylalanine is primarily used in the pharmaceutical industry for the synthesis of various bioactive compounds. It also finds applications in the polymer industry for the development of novel materials with specific properties. Additionally, it is explored in the fields of sensors and semiconductors for its unique chemical and biological characteristics.

When handling 2-Fluoro-D-phenylalanine, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.