1,2-Butanediol(CAS: 26171-83-5)

1,2-Butanediol, also known as 1,2-butanediol (CAS: 26171-83-5), is a colorless, viscous liquid with a mild alcohol odor. It has a molecular weight of 76.11 g/mol. This compound is slightly soluble in water but more soluble in organic solvents. Chemically, it is highly reactive and can undergo addition reactions, esterification, and condensation. It is used in the synthesis of polyurethanes, plasticizers, and pharmaceuticals.

1,2-Butanediol (CAS: 26171-83-5) is typically synthesized by the hydrogenation of maleic anhydride or succinic anhydride, catalyzed by a metal catalyst such as Raney nickel. Alternatively, it can be prepared by the hydrolysis of dibutyl ketone. The process yields a mixture of isomers, and selective hydrogenation is required to separate the desired 1,2-isomer from the 1,4-isomer. The yield can reach up to 90%.

1,2-Butanediol (CAS: 26171-83-5) is widely used in the pharmaceutical, polymer, and chemical industries. In pharmaceuticals, it is a key intermediate for the production of certain drugs. In polymers, it serves as a monomer in the synthesis of polyurethanes and polyesters. Additionally, it is utilized in the production of plasticizers, adhesives, and as a solvent in various applications.

When handling 1,2-Butanediol (CAS: 26171-83-5), appropriate personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat should be worn. It should be stored in a well-ventilated area away from heat sources and strong oxidizers. Spills should be handled carefully with appropriate tools to avoid skin contact. In case of exposure, seek medical attention immediately. Always refer to the safety data sheet (SDS) for detailed handling instructions and emergency procedures.