Compound Q&A

How is 1,2-Butanediol (CAS: 26171-83-5) typically synthesized?

Answer

1,2-Butanediol
1,2-Butanediol (CAS: 26171-83-5) is typically synthesized by the hydrogenation of maleic anhydride or succinic anhydride, catalyzed by a metal catalyst such as Raney nickel. Alternatively, it can be prepared by the hydrolysis of dibutyl ketone. The process yields a mixture of isomers, and selective hydrogenation is required to separate the desired 1,2-isomer from the 1,4-isomer. The yield can reach up to 90%.

About

CAS No 26171-83-5
English Name 1,2-Butanediol
Molecular Formula C4H10O2
Molecular Weight 90.12 g/mol
SMILES CCC(CO)O
InChIKey BMRWNKZVCUKKSR-UHFFFAOYSA-N
Last Updated: 2025-10-22 19:24

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