4-Pyrimidinol(CAS: 51953-18-5)

4-Pyrimidinol (CAS: 51953-18-5) is a white crystalline solid with a molecular weight of 106.12 g/mol. It has a solubility of 3 g/L in water and is slightly soluble in ethanol. It is least reactive towards strong acids and bases, but can undergo nucleophilic substitution and condensation reactions.

4-Pyrimidinol can be synthesized through the reduction of 4-pyrimidone with lithium aluminum hydride (LAH) as a reducing agent. The reaction is conducted under anhydrous conditions to ensure purity and high yield. Alternative methods include hydrogenation of 4-pyridone-2-carbaldehyde.

4-Pyrimidinol is used in the pharmaceutical industry for the synthesis of antiviral drugs and as an intermediate in the production of other organic compounds. It also finds applications in the polymer industry for the development of advanced materials and in the electronics industry for semiconductor applications.

When handling 4-Pyrimidinol (CAS: 51953-18-5), it is crucial to wear personal protective equipment (PPE) such as gloves and safety glasses. Store it in a well-ventilated area and use a fume hood during operations to minimize inhalation. In case of a spill, neutralize with an appropriate acid or base and dispose of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed information.