4'-bromo-[1,1'-Biphenyl]-4-carbonitrile(CAS: 57774-35-3)

4'-Bromo-[1,1'-Biphenyl]-4-carbonitrile is a crystalline solid with a molecular weight of approximately 319.07 g/mol. It has low water solubility but is soluble in organic solvents like dimethylformamide and acetonitrile. It is moderately reactive, particularly towards nucleophiles and bases. The compound is stable under normal conditions but should be handled with care to avoid prolonged exposure to moisture or heat.

4'-Bromo-[1,1'-Biphenyl]-4-carbonitrile is typically synthesized via the nitration of biphenyl followed by bromination and hydrolysis. Commonly, bromination is performed using bromine in the presence of a solvent like chloroform. Precise control over reaction conditions ensures high selectivity and yield, typically around 80-90%.

4'-Bromo-[1,1'-Biphenyl]-4-carbonitrile is used in the pharmaceuticals industry for the synthesis of certain drug intermediates. It also finds applications in the polymer industry for the development of novel materials. Additionally, it is utilized in the semiconductor sector for manufacturing electronic components and sensors due to its unique chemical properties.

Proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn when handling 4'-bromo-[1,1'-Biphenyl]-4-carbonitrile. Work should be conducted in a well-ventilated fume hood to minimize inhalation risks. Spills should be managed with appropriate absorbents and disposed of according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.