Compound Q&A

How is 4'-bromo-[1,1'-Biphenyl]-4-carbonitrile (CAS: 57774-35-3) typically synthesized?

Answer

4'-bromo-[1,1'-Biphenyl]-4-carbonitrile
4'-Bromo-[1,1'-Biphenyl]-4-carbonitrile is typically synthesized via the nitration of biphenyl followed by bromination and hydrolysis. Commonly, bromination is performed using bromine in the presence of a solvent like chloroform. Precise control over reaction conditions ensures high selectivity and yield, typically around 80-90%.

About

CAS No 57774-35-3
English Name 4'-bromo-[1,1'-Biphenyl]-4-carbonitrile
Molecular Formula C13H8BrN
Molecular Weight 258.11 g/mol
SMILES C1=CC(=CC=C1C#N)C2=CC=C(C=C2)Br
InChIKey BHVHKOVPWZKVCC-UHFFFAOYSA-N
Last Updated: 2025-11-04 22:31

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