(3beta)-3-Hydroxychol-5-en-24-oic acid(CAS: 5255-17-4)

(3beta)-3-Hydroxychol-5-en-24-oic acid is a solid at room temperature with a molecular weight of approximately 364.48 g/mol. It has a solubility in water of 0.01 g/L and is slightly soluble in ethanol. This compound is moderately reactive, especially towards nucleophiles and bases. It is stable under anhydrous conditions but should be protected from moisture and air exposure.

(3beta)-3-Hydroxychol-5-en-24-oic acid is usually synthesized via reduction of 24-oxochol-5-en-3-one with sodium borohydride followed by hydrolysis under basic conditions. The reaction is highly selective and yields up to 90% of the desired product. The process requires careful control of pH and temperature to achieve high purity.

(3beta)-3-Hydroxychol-5-en-24-oic acid is utilized in the pharmaceutical industry for the development of cholesterol-related drugs. It is also used in the polymer industry for the modification of polymer properties and in semiconductor technology for research purposes. Additionally, it has potential applications in the sensor industry for the development of biosensors.

When handling (3beta)-3-Hydroxychol-5-en-24-oic acid, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and moisture. In case of a spill, it is recommended to use a fume hood and clean up with appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.