4-Methyl-1,3-benzenediol(CAS: 496-73-1)

4-Methyl-1,3-benzenediol (CAS: 496-73-1) is a white, crystalline solid with a molecular weight of 143.16 g/mol. It has a solubility of 1.22 g/100 mL in water and is slightly soluble in ethanol. This compound is reactive, particularly towards nucleophilic substitution reactions. It exhibits a pKa of around 11.2 and is used in various industrial applications due to its chemical stability and reactivity.

4-Methyl-1,3-benzenediol (CAS: 496-73-1) can be synthesized through a classic reduction of the corresponding benzenedicarboxylic acid using sodium borohydride. The reaction is carried out in an aqueous medium, and the use of a high-purity reducing agent is crucial for obtaining high yield and selectivity. The process is typically conducted under gentle conditions to maintain the structural integrity of the product.

4-Methyl-1,3-benzenediol (CAS: 496-73-1) is utilized in various industries. It is commonly found in pharmaceuticals for its intermediate role in drug synthesis, in polymers for its stabilizing properties, and in sensors for its reactivity to certain analytes. Additionally, it is used in semiconductor applications due to its electron-donating ability, enhancing the performance of certain devices.

When handling 4-Methyl-1,3-benzenediol (CAS: 496-73-1), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.