5,6-Dimethyl-1-indanone(CAS: 16440-97-4)

5,6-Dimethyl-1-indanone (CAS: 16440-97-4) is a colorless liquid with a molecular weight of 130.18 g/mol. It has a melting point of -42°C and a boiling point of 200°C. This compound is sparingly soluble in water but fully miscible with common organic solvents. It is mildly reactive and can undergo condensation reactions under certain conditions.

5,6-Dimethyl-1-indanone can be synthesized through the Wittig reaction where methyl iodide is reacted with indanone in the presence of a phosphonium salt. Alternatively, it can be prepared by the oxidation of 5,6-dimethylindan, often using a combination of sodium hypochlorite and sodium hydroxide under controlled conditions to ensure high selectivity and yield.

5,6-Dimethyl-1-indanone (CAS: 16440-97-4) is primarily used in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also utilized in the production of sensors and semiconductors as a precursor material. Additionally, it plays a role in the development of polymer-based materials, although its specific applications in this field are limited.

When handling 5,6-Dimethyl-1-indanone (CAS: 16440-97-4), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. This compound should be stored in a cool, dry place, away from direct sunlight and heat sources. In the event of a spill, use appropriate absorbents to contain the spill and dispose of them according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.