Compound Q&A

How is 5,6-Dimethyl-1-indanone (CAS: 16440-97-4) typically synthesized?

Answer

5,6-Dimethyl-1-indanone
5,6-Dimethyl-1-indanone can be synthesized through the Wittig reaction where methyl iodide is reacted with indanone in the presence of a phosphonium salt. Alternatively, it can be prepared by the oxidation of 5,6-dimethylindan, often using a combination of sodium hypochlorite and sodium hydroxide under controlled conditions to ensure high selectivity and yield.

About

CAS No 16440-97-4
English Name 5,6-Dimethyl-1-indanone
Molecular Formula C11H12O
Molecular Weight 160.22 g/mol
SMILES CC1=CC2=C(C=C1C)C(=O)CC2
InChIKey ZAZMJPVXTZEDDN-UHFFFAOYSA-N
Last Updated: 2025-11-05 07:29

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