2,4-Dibromoquinazoline(CAS: 872998-61-3)

2,4-Dibromoquinazoline is a crystalline solid with a molecular weight of approximately 286.04 g/mol. It has poor water solubility but is soluble in common organic solvents such as dichloromethane and acetonitrile. Chemically, it is relatively unreactive but can undergo substitution reactions under certain conditions. Its high molecular weight and low solubility make it suitable for various applications in organic synthesis and materials science.

2,4-Dibromoquinazoline is typically synthesized via a multi-step process involving the bromination of quinazoline. The reaction is usually carried out under anhydrous conditions using reagents like N-bromosuccinimide (NBS) and a suitable catalyst such as azobisisobutyronitrile (AIBN). The yield is generally around 70-80%, and the method provides good selectivity for the desired brominated product.

2,4-Dibromoquinazoline (CAS: 872998-61-3) is used in a variety of industries, including pharmaceuticals, where it can serve as a precursor in the synthesis of novel drugs. It also finds applications in the development of sensors and semiconductors due to its unique electronic properties. Additionally, it is utilized in the production of advanced materials for various technological applications.

When handling 2,4-Dibromoquinazoline (CAS: 872998-61-3), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. In case of a spill, it should be carefully cleaned up using appropriate absorbent materials, and the area should be thoroughly rinsed. Handling should be done with care due to its crystalline form and potential reactivity in certain conditions. Refer to the Safety Data Sheet (SDS) for detailed safety information.