Compound Q&A

How is 2,4-Dibromoquinazoline (CAS: 872998-61-3) typically synthesized?

Answer

2,4-Dibromoquinazoline
2,4-Dibromoquinazoline is typically synthesized via a multi-step process involving the bromination of quinazoline. The reaction is usually carried out under anhydrous conditions using reagents like N-bromosuccinimide (NBS) and a suitable catalyst such as azobisisobutyronitrile (AIBN). The yield is generally around 70-80%, and the method provides good selectivity for the desired brominated product.

About

English Name 2,4-Dibromoquinazoline
Molecular Formula C8H4Br2N2
Molecular Weight 287.94 g/mol
SMILES Brc1nc2ccccc2c(n1)Br
InChIKey CDBAGRHVFMGOON-UHFFFAOYSA-N
Last Updated: 2025-11-07 15:33

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