2,2-Dichloro-1-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethanone(CAS: 71526-07-3)

2,2-Dichloro-1-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethanone (CAS: 71526-07-3) is a solid with a crystalline form at room temperature. Its molecular weight is approximately 267.07 g/mol. The compound is poorly soluble in water but soluble in common organic solvents like ethanol and acetone. It is moderately reactive and can undergo nucleophilic substitution reactions. Chemically, it is stable under normal conditions but should be stored away from moisture and direct sunlight.

2,2-Dichloro-1-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethanone (CAS: 71526-07-3) is typically synthesized via the condensation of 1-oxa-4-azaspiro[4.5]dec-4-yl alcohol with chloroacetyl chloride. The reaction proceeds in the presence of a catalytic amount of a base like triethylamine. The product is obtained with good yield and selectivity, and the process is scalable for industrial applications.

2,2-Dichloro-1-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethanone (CAS: 71526-07-3) is primarily used in the pharmaceutical industry for the synthesis of various drug candidates. It is also utilized in the polymer industry for the modification of polymer properties. Additionally, it finds applications in the development of sensors and semiconductors due to its unique chemical structure.

When handling 2,2-Dichloro-1-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethanone (CAS: 71526-07-3), safety measures include wearing appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be used in a well-ventilated area or a fume hood to avoid inhalation. In case of a spill, neutralize the spill with an appropriate solvent and dispose of it according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed information on handling and emergency procedures.