2,4,6-Trichloro-5-methylpyrimidine(CAS: 1780-36-5)

2,4,6-Trichloro-5-methylpyrimidine (CAS: 1780-36-5) is a crystalline solid with a molecular weight of approximately 218.04 g/mol. It has a low solubility in water but is more soluble in organic solvents. This compound is relatively unreactive under normal conditions but can undergo nucleophilic substitution reactions. It is commonly used in the pharmaceutical and agricultural industries due to its chemical stability and reactivity.

2,4,6-Trichloro-5-methylpyrimidine (CAS: 1780-36-5) is typically synthesized through the reaction of 5-chlorocarbonylpyrimidine with methyl chloride in the presence of a strong base such as sodium hydride. This method provides high selectivity and yield, making it a preferred route for industrial production.

2,4,6-Trichloro-5-methylpyrimidine (CAS: 1780-36-5) is widely used in the pharmaceutical industry for the synthesis of antifungal drugs. It is also applied in the agricultural sector as a herbicide component. Additionally, it has potential applications in the polymer industry for the development of new materials with specific properties.

When handling 2,4,6-Trichloro-5-methylpyrimidine (CAS: 1780-36-5), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Work should be carried out in a well-ventilated area or a fume hood to prevent inhalation. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly washed. Always consult the safety data sheet (SDS) for detailed information and guidelines.