Compound Q&A

How is 2,4,6-Trichloro-5-methylpyrimidine (CAS: 1780-36-5) typically synthesized?

Answer

2,4,6-Trichloro-5-methylpyrimidine
2,4,6-Trichloro-5-methylpyrimidine (CAS: 1780-36-5) is typically synthesized through the reaction of 5-chlorocarbonylpyrimidine with methyl chloride in the presence of a strong base such as sodium hydride. This method provides high selectivity and yield, making it a preferred route for industrial production.

About

CAS No 1780-36-5
English Name 2,4,6-Trichloro-5-methylpyrimidine
Molecular Formula C5H3Cl3N2
Molecular Weight 197.45 g/mol
SMILES CC1=C(N=C(N=C1Cl)Cl)Cl
InChIKey VTSWSQGDJQFXHB-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48

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