(2R)-2-Methylpyrrolidine hydrochloride (1:1)(CAS: 135324-85-5)

(2R)-2-Methylpyrrolidine hydrochloride is a colorless to white crystalline solid with a molecular weight of 138.65 g/mol. It has a solubility of 100 mg/mL in water and 50 mg/mL in ethanol. This compound is mildly basic due to its hydrochloride salt form, and it reacts with bases to form pyrrolidine. It is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

(2R)-2-Methylpyrrolidine hydrochloride is commonly synthesized by the reaction of 2-methylpyrrolidine with hydrochloric acid. The reaction typically proceeds at room temperature, and the yield is around 85-90%. The use of a catalytic amount of acid can enhance the selectivity and yield of the product.

(2R)-2-Methylpyrrolidine hydrochloride is used in various industries, including pharmaceuticals where it serves as a precursor for drug synthesis, in polymer science for the production of functional polymers, and in the manufacturing of chemical sensors and semiconductors. Its basic nature and structural features make it suitable for these applications.

When handling (2R)-2-Methylpyrrolidine hydrochloride, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be used in a well-ventilated area or under a fume hood to avoid inhalation. In case of a spill, neutralize the acid with a base and dispose of it according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.