Compound Q&A

How is (2R)-2-Methylpyrrolidine hydrochloride (CAS: 135324-85-5) typically synthesized?

Answer

(2R)-2-Methylpyrrolidine hydrochloride (1:1)
(2R)-2-Methylpyrrolidine hydrochloride is commonly synthesized by the reaction of 2-methylpyrrolidine with hydrochloric acid. The reaction typically proceeds at room temperature, and the yield is around 85-90%. The use of a catalytic amount of acid can enhance the selectivity and yield of the product.

About

English Name (2R)-2-Methylpyrrolidine hydrochloride (1:1)
Molecular Formula C5H12ClN
Molecular Weight 121.61 g/mol
SMILES CC1CCCN1.Cl
InChIKey JNEIFWYJFOEKIM-NUBCRITNSA-N
Last Updated: 2025-10-17 07:35

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