6-O-alpha-D-Glucosyl-beta-cyclodextrin(CAS: 92517-02-7)

6-O-alpha-D-Glucosyl-beta-cyclodextrin is a white to off-white crystalline powder with a molecular weight of approximately 1458.86 g/mol. It is slightly soluble in water and is known for its ability to form inclusion complexes. Chemically, it shows good stability in acidic and neutral conditions but is less stable in basic solutions. It is not reactive with common reagents and is generally considered safe for laboratory use.

6-O-alpha-D-Glucosyl-beta-cyclodextrin is typically synthesized through a glucosylation reaction. This involves the transfer of a glucose molecule to a beta-cyclodextrin molecule using a reducing sugar and a suitable catalyst, such as sodium hydride or a borohydride. The reaction is conducted in an aqueous medium, and the yield is generally good, with selectivity for the alpha-D-glucosyl derivative being high.

6-O-alpha-D-Glucosyl-beta-cyclodextrin is used primarily in the pharmaceutical and food industries. In the pharmaceutical sector, it is used as a stabilizer, a carrier for active ingredients, and a complexing agent. In the food industry, it serves as a stabilizer and a texturizing agent. It is also used in the cosmetic and polymer industries for its unique physicochemical properties.

When handling 6-O-alpha-D-Glucosyl-beta-cyclodextrin, basic laboratory safety precautions should be followed. Wear appropriate personal protective equipment (PPE), such as gloves and safety goggles. Work in a well-ventilated area or fume hood to minimize inhalation risks. Ensure the compound is stored in a cool, dry place away from direct sunlight. In case of spill, neutralize with water and dispose of according to local regulations. Always refer to the safety data sheet (SDS) for detailed handling and emergency procedures.