1,3-Dichloro-2-fluoro-4-nitrobenzene(CAS: 393-79-3)

1,3-Dichloro-2-fluoro-4-nitrobenzene (CAS: 393-79-3) is a crystalline solid with a molecular weight of approximately 244.04 g/mol. It has a melting point of 117-119°C and a low solubility in water (0.5 g/100 mL at 25°C). It is highly reactive with reducing agents and can undergo substitution reactions.

1,3-Dichloro-2-fluoro-4-nitrobenzene (CAS: 393-79-3) is synthesized through a multi-step process involving the nitration of 2-fluoro-4-chlorobenzene, followed by chlorination at the 3-position. This can be achieved using nitric acid and sulfuric acid as reagents, with a yield of about 80% and good selectivity.

1,3-Dichloro-2-fluoro-4-nitrobenzene (CAS: 393-79-3) is used in pharmaceuticals for the synthesis of various intermediates and in the manufacturing of dyes and pigments. It also finds applications in the agricultural industry as a herbicide precursor and in the electronics industry as a photoresist material.

When handling 1,3-Dichloro-2-fluoro-4-nitrobenzene (CAS: 393-79-3), proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. It should be handled in a fume hood to avoid inhalation. In case of a spill, it should be cleaned up using absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.