Compound Q&A

How is 1,3-Dichloro-2-fluoro-4-nitrobenzene (CAS: 393-79-3) typically synthesized?

Answer

1,3-Dichloro-2-fluoro-4-nitrobenzene
1,3-Dichloro-2-fluoro-4-nitrobenzene (CAS: 393-79-3) is synthesized through a multi-step process involving the nitration of 2-fluoro-4-chlorobenzene, followed by chlorination at the 3-position. This can be achieved using nitric acid and sulfuric acid as reagents, with a yield of about 80% and good selectivity.

About

CAS No 393-79-3
English Name 1,3-Dichloro-2-fluoro-4-nitrobenzene
Molecular Formula C6H2Cl2FNO2
Molecular Weight 209.99 g/mol
SMILES C1=CC(=C(C(=C1[N+](=O)[O-])Cl)F)Cl
InChIKey JSEVUBOYVADSHX-UHFFFAOYSA-N
Last Updated: 2025-09-28 13:06

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