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O-[4-nitro-2-(trifluoromethyl)phenyl]hydroxylamine(CAS: 94832-15-2)

O-[4-nitro-2-(trifluoromethyl)phenyl]hydroxylamine
CAS Number

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Basic Information

Molecular Formula
C7H5F3N2O3
Molecular Weight
222.12 g/mol

Physical Properties

Density
1.521±0.06 g/cm3 (20 ºC 760 Torr),

Chemical Identifiers

SMILES
C1=CC(=C(C=C1[N+](=O)[O-])C(F)(F)F)ON
InChIKey
KIEHAOBEQSYFRF-UHFFFAOYSA-N

Database References

MDL Number
MFCD18070977

FAQ

O-[4-nitro-2-(trifluoromethyl)phenyl]hydroxylamine (CAS: 94832-15-2) is a white or off-white crystalline solid. It has a molecular weight of approximately 326.15 g/mol and is slightly soluble in water. The compound is highly reactive due to the presence of the nitro and trifluoromethyl groups. It shows good stability under normal conditions but can react with reducing agents or strong bases.
O-[4-nitro-2-(trifluoromethyl)phenyl]hydroxylamine is typically synthesized by the trifluoromethylation of 4-nitrobenzaldehyde followed by hydroxylation. The reaction involves the use of trifluoromethylation reagents and an appropriate catalyst to achieve high yield and selectivity. The hydroxylation step is carried out under controlled conditions to ensure the formation of the desired product.
O-[4-nitro-2-(trifluoromethyl)phenyl]hydroxylamine (CAS: 94832-15-2) is primarily used in the pharmaceutical industry for the synthesis of other compounds. It also finds applications in the polymer industry for the modification of polymer properties. Additionally, it is used in the development of sensors and as a precursor in semiconductor manufacturing processes.
When handling O-[4-nitro-2-(trifluoromethyl)phenyl]hydroxylamine (CAS: 94832-15-2), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be handled with caution using absorbent materials and disposed of according to local regulations. Always refer to the material safety data sheet (MSDS) for detailed safety information and guidelines.

Safety Notice

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