1-Bromo-4-cyclohexylbenzene(CAS: 25109-28-8)

1-Bromo-4-cyclohexylbenzene (CAS: 25109-28-8) is a solid crystalline compound with a molecular weight of approximately 215.12 g/mol. It has a low solubility in water but is soluble in common organic solvents like ethanol and dichloromethane. Chemically, it is reactive towards nucleophiles and electrophiles. It is a brominated derivative of benzene with a cyclohexyl substituent, making it useful in organic synthesis and as a precursor for various functionalized compounds.

1-Bromo-4-cyclohexylbenzene (CAS: 25109-28-8) is typically synthesized via a substitution reaction. The common method involves reacting bromobenzene with cyclohexylmagnesium bromide in a Grignard reaction. The reaction is highly selective, and the yield can be over 90%. This method requires anhydrous conditions and is often carried out in anhydrous tetrahydrofuran (THF).

1-Bromo-4-cyclohexylbenzene (CAS: 25109-28-8) is primarily used in organic synthesis as a precursor for pharmaceuticals, polymers, and sensors. Its cyclohexyl group makes it useful in the development of molecules with specific physical and chemical properties. Additionally, it can be used in the synthesis of semiconducting materials and electronic devices.

When handling 1-Bromo-4-cyclohexylbenzene (CAS: 25109-28-8), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbent materials. Always consult the safety data sheet (SDS) for detailed handling and storage instructions. Keep the compound away from heat and sparks, as it may release bromine vapor, which is toxic and reactive.