Compound Q&A
How is 1-Bromo-4-cyclohexylbenzene (CAS: 25109-28-8) typically synthesized?
Answer
1-Bromo-4-cyclohexylbenzene (CAS: 25109-28-8) is typically synthesized via a substitution reaction. The common method involves reacting bromobenzene with cyclohexylmagnesium bromide in a Grignard reaction. The reaction is highly selective, and the yield can be over 90%. This method requires anhydrous conditions and is often carried out in anhydrous tetrahydrofuran (THF).
About
CAS No
25109-28-8
English Name
1-Bromo-4-cyclohexylbenzene
Molecular Formula
C12H15Br
Molecular Weight
239.16 g/mol
SMILES
C1CCC(CC1)C2=CC=C(C=C2)Br
InChIKey
LVIJLEREXMVRAN-UHFFFAOYSA-N
Last Updated: 2025-10-13 11:18