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4-Amino-5-chloro-2-methoxybenzoic acid(CAS: 7206-70-4)

4-Amino-5-chloro-2-methoxybenzoic acid
CAS Number

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Basic Information

Molecular Formula
C8H8ClNO3
Molecular Weight
201.61 g/mol

Physical Properties

Melting Point
206 °C (dec.) (lit.)
Boiling Point
369.7°C at 760 mmHg
Density
1.3639 (rough estimate)
Flash Point
177.4°C

Chemical Identifiers

SMILES
COC1=CC(=C(C=C1C(=O)O)Cl)N
InChIKey
RVEATKYEARPWRE-UHFFFAOYSA-N

Database References

MDL Number
MFCD00038794

FAQ

4-Amino-5-chloro-2-methoxybenzoic acid is a crystalline solid with a molecular weight of approximately 241.62 g/mol. It has a solubility of about 10 mg/mL in water. This compound is relatively stable but can react with bases. It exhibits weak acidic properties and has limited reactivity under normal conditions.
4-Amino-5-chloro-2-methoxybenzoic acid is typically synthesized through the reaction of 2-chloro-5-methoxybenzoic acid with an amine, such as ammonia or aniline, followed by acidification. Common solvents include methanol or ethanol, and the reaction is usually carried out under mild conditions to achieve good selectivity and yield.
4-Amino-5-chloro-2-methoxybenzoic acid is primarily used in the pharmaceutical industry as an intermediate in the synthesis of certain medications. It is also utilized in the production of sensors and as a component in some polymers and semiconductors.
When handling 4-Amino-5-chloro-2-methoxybenzoic acid, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Fume hoods should be used during operations to minimize exposure. Spills should be cleaned up according to the Material Safety Data Sheet (MSDS/SDS). Proper storage in a cool, dry place away from strong acids and bases is recommended.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

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