4-Amino-5-chloro-2-methoxybenzoic acid

Basic Information

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CAS Number

7206-70-4

Molecular Formula

C8H8ClNO3

Molecular Weight

201.61 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

206 °C (dec.)

Boiling Point

369.7°C at 760 mmHg

Density

1.3639 (rough estimate)

Flash Point

177.4°C

Refractive Index

1.5800 (estimate)

SMILES

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COC1=CC(=C(C=C1C(=O)O)Cl)N

InChI

InChI=1S/C8H8ClNO3/c1-13-7-3-6(10)5(9)2-4(7)8(11)12/h2-3H,10H2,1H3,(H,11,12)

InChIKey

RVEATKYEARPWRE-UHFFFAOYSA-N

LogP

1.629

Topological Polar Surface Area

72.55 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

200

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

7206-70-4
4-amino 2-methoxy 5-chloro benzoic acid
4amino-5-chloro-2-methoxy-benzoic acid
MFCD00038794
2-methoxy-4-amino-5-chloro benzoic acid
HMS1534L01
SB78427
BRD-K18838510-001-01-9
4-Amino-5-Chloro-2-Methoxyl Benzoic Acid
Q27286706
AM84150
2-methoxy-4-amino-5-chlorobenzoic acid
PD013684
Benzoic acid, 4-amino-5-chloro-2-methoxy-
FS-4061
UNII-PQ8L2L84EL
PQ8L2L84EL
F14881
5-CHLORO-4-AMINO-2-ETHOXYBENZOIC ACID
CS-0128743
EU-0018508
5-Chloro-4-amino-2-methoxybenzoic acid
Benzoic acid,4-amino-5-chloro-2-hydroxy-
EN300-20545
TimTec1_000243
4-amino-5-chloro-2-methoxy benzoic acid
Metoclopramide EP Impurity C
4-Amino-5-chloro-2-methoxybenzoic acid, 95%
InChI=1/C8H8ClNO3/c1-13-7-3-6(10)5(9)2-4(7)8(11)12/h2-3H,10H2,1H3,(H,11,12
A1237
NS00037326

MDL Number

MFCD00038794

Customs Code

2922509090

FAQ

What are the physical and chemical properties of 4-Amino-5-chloro-2-methoxybenzoic acid (CAS: 7206-70-4)?

4-Amino-5-chloro-2-methoxybenzoic acid is a crystalline solid with a molecular weight of approximately 241.62 g/mol. It has a solubility of about 10 mg/mL in water. This compound is relatively stable but can react with bases. It exhibits weak acidic properties and has limited reactivity under normal conditions.

How is 4-Amino-5-chloro-2-methoxybenzoic acid (CAS: 7206-70-4) typically synthesized?

4-Amino-5-chloro-2-methoxybenzoic acid is typically synthesized through the reaction of 2-chloro-5-methoxybenzoic acid with an amine, such as ammonia or aniline, followed by acidification. Common solvents include methanol or ethanol, and the reaction is usually carried out under mild conditions to achieve good selectivity and yield.

What industries use 4-Amino-5-chloro-2-methoxybenzoic acid (CAS: 7206-70-4)?

4-Amino-5-chloro-2-methoxybenzoic acid is primarily used in the pharmaceutical industry as an intermediate in the synthesis of certain medications. It is also utilized in the production of sensors and as a component in some polymers and semiconductors.

What precautions should be taken when handling 4-Amino-5-chloro-2-methoxybenzoic acid (CAS: 7206-70-4)?

When handling 4-Amino-5-chloro-2-methoxybenzoic acid, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Fume hoods should be used during operations to minimize exposure. Spills should be cleaned up according to the Material Safety Data Sheet (MSDS/SDS). Proper storage in a cool, dry place away from strong acids and bases is recommended.