4-(4-Ethyl-1-piperazinyl)benzoic acid(CAS: 784130-66-1)

4-(4-Ethyl-1-piperazinyl)benzoic acid is a white crystalline solid with a molecular weight of approximately 222.27 g/mol. It has a pKa of about 3.4 and is slightly soluble in water. This compound shows moderate reactivity, particularly in acidic conditions, and is stable under normal storage conditions.

4-(4-Ethyl-1-piperazinyl)benzoic acid is typically synthesized by the coupling of 4-aminobenzoic acid with 4-ethylpiperazine followed by acylation. This process involves the use of a Lewis acid catalyst, such as aluminum chloride, and yields a product with high structural integrity and purity.

4-(4-Ethyl-1-piperazinyl)benzoic acid is primarily used in the pharmaceutical industry as a precursor to drug synthesis. It is also utilized in the polymer industry for the development of novel materials and in the sensor industry for the fabrication of chemical sensors.

When handling 4-(4-Ethyl-1-piperazinyl)benzoic acid, it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. This compound should be used in a well-ventilated area or a fume hood. In case of a spill, it is crucial to clean it up using appropriate absorbents and to follow the Material Safety Data Sheet (MSDS) guidelines for disposal.