5-O-Benzyl-2,3-O-isopropylidene-D-ribono-1,4-lactone(CAS: 85846-80-6)

5-O-Benzyl-2,3-O-isopropylidene-D-ribono-1,4-lactone (CAS: 85846-80-6) is a white crystalline solid with a molecular weight of approximately 286.3 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. The compound shows moderate reactivity with hydroxyl compounds and exhibits stability under neutral conditions.

5-O-Benzyl-2,3-O-isopropylidene-D-ribono-1,4-lactone is commonly synthesized through a condensation reaction between D-ribonolactone and benzyl bromide in the presence of a phosphine-based organocatalyst. The reaction yields a high purity product with good selectivity and moderate yield under mild conditions.

5-O-Benzyl-2,3-O-isopropylidene-D-ribono-1,4-lactone (CAS: 85846-80-6) is primarily utilized in the pharmaceutical industry for the synthesis of certain biologically active compounds. It also finds application in the production of functional polymers and as a reagent in organic synthesis for its structural features.

When handling 5-O-Benzyl-2,3-O-isopropylidene-D-ribono-1,4-lactone (CAS: 85846-80-6), it is crucial to use appropriate personal protective equipment (PPE) such as gloves and safety glasses. It should be stored in a cool, dry place away from direct sunlight. Spills should be cleaned up immediately according to a well-prepared safety data sheet (SDS) to ensure safety.