6-Hydroxyisoindolin-1-one(CAS: 659737-57-2)

6-Hydroxyisoindolin-1-one (CAS: 659737-57-2) is a white crystalline solid with a molecular weight of approximately 160.15 g/mol. It has a solubility of about 10 mg/mL in water and low solubility in organic solvents like acetone and ethanol. Chemically, it is an unstable compound that readily undergoes hydrolysis and reduction reactions.

6-Hydroxyisoindolin-1-one (CAS: 659737-57-2) is commonly synthesized via the condensation of isoindoline-1,3-dione with hydroxylamine hydrochloride. The reaction is carried out under acidic conditions, and the yield can be improved with the use of a catalyst such as acetic acid. The reaction is selective and yields up to 90% product.

6-Hydroxyisoindolin-1-one (CAS: 659737-57-2) finds applications in the pharmaceutical industry as a precursor for the synthesis of various bioactive compounds. It is also used in the polymer industry for the development of functional materials and in the semiconductor industry for the production of photoresists and other electronic materials.

When handling 6-Hydroxyisoindolin-1-one (CAS: 659737-57-2), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or under a fume hood. In case of a spill, refer to the safety data sheet (SDS) for instructions on proper cleanup procedures to prevent inhalation and skin contact.