4-Amino-5-hydroxy-2,7-naphthalenedisulfonic acid(CAS: 8011-86-7)

4-Amino-5-hydroxy-2,7-naphthalenedisulfonic acid is a crystalline solid with a molecular weight of approximately 366.14 g/mol. It is soluble in water, with a solubility of around 10 g/L. Chemically, it is highly reactive due to the presence of sulfonic acid groups, which can participate in various chemical reactions such as esterification and condensation. It has a melting point of around 350°C and a pKa value of approximately 2.6.

4-Amino-5-hydroxy-2,7-naphthalenedisulfonic acid is usually synthesized through the sulfonation of 4-amino-5-hydroxy-2,7-naphthalenedicarboxylic acid. This process can be catalyzed by sulfuric acid, with a yield of about 85-90%. The reaction involves the introduction of two sulfonic acid groups to the naphthalene ring, followed by a careful dehydration step to obtain the final product.

4-Amino-5-hydroxy-2,7-naphthalenedisulfonic acid is primarily used in the pharmaceutical industry for the synthesis of dyes and pigments, as well as in the production of sensors and semiconductors. It is also utilized in the polymer industry for the modification of polymer properties and in analytical chemistry for various spectroscopic applications due to its chromophoric nature.

When handling 4-Amino-5-hydroxy-2,7-naphthalenedisulfonic acid, it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place, away from direct sunlight and heat sources. In case of a spill, it should be cleaned up using appropriate absorbents, and the area should be thoroughly rinsed. Always consult the safety data sheet (SDS) for specific handling and disposal instructions.