2-(2-Furyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(CAS: 374790-93-9)

2-(2-Furyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 374790-93-9) has a crystalline form with a molecular weight of approximately 252.27 g/mol. It is slightly soluble in water but soluble in organic solvents like dichloromethane and methanol. The compound is known for its reactivity in organoboron coupling reactions, particularly in the presence of palladium catalysts.

2-(2-Furyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 374790-93-9) is typically synthesized through the reaction of 2-bromofurandione with tetramethyl-1,3,2-dioxaborolane, facilitated by a palladium catalyst in the presence of a base. The reaction provides good yield and selectivity.

2-(2-Furyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 374790-93-9) is used in the pharmaceutical industry for the synthesis of various bioactive compounds, as well as in the polymer industry for the development of functional materials with enhanced properties. It is also utilized in sensor technology and semiconductor manufacturing for specific chemical reactions.

When handling 2-(2-Furyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 374790-93-9), it is essential to use personal protective equipment (PPE) such as gloves and safety goggles. The substance should be stored in a well-ventilated area and handled in a fume hood to minimize inhalation risks. In case of a spill, the area should be cleaned immediately with the appropriate cleaning agents. Always consult the Safety Data Sheet (SDS) for detailed safety information.