5-Bromo-6-fluoro-1H-benzo[d]imidazole(CAS: 1008360-84-6)

5-Bromo-6-fluoro-1H-benzo[d]imidazole (CAS: 1008360-84-6) is a crystalline solid with a molecular weight of approximately 245.03 g/mol. It is slightly soluble in water and ethanol. Chemically, it is highly reactive towards nucleophiles and can undergo various substitution reactions. It is stable under normal conditions but should be stored in a fume hood to avoid inhalation exposure.

5-Bromo-6-fluoro-1H-benzo[d]imidazole (CAS: 1008360-84-6) is synthesized by the bromination and fluorination of 1H-benzo[d]imidazole or its derivatives. Common methods include using N-bromosuccinimide (NBS) and N-fluorobencenesulfonimide (NFBS) as catalysts. The yield and selectivity depend on the reaction conditions and the choice of reagents.

5-Bromo-6-fluoro-1H-benzo[d]imidazole (CAS: 1008360-84-6) is primarily used in pharmaceuticals for developing drugs targeting specific molecular pathways. It is also utilized in the synthesis of fluorescent dyes and sensors for detecting specific compounds. Additionally, it has applications in the semiconductor industry for creating thin-film coatings.

When handling 5-Bromo-6-fluoro-1H-benzo[d]imidazole (CAS: 1008360-84-6), always wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a well-ventilated area and use a fume hood during operations to prevent inhalation exposure. In case of a spill, immediately clean up with appropriate absorbent materials and dispose of according to safety guidelines. Refer to the Safety Data Sheet (SDS) for detailed safety information.