2-(Benzyloxy)-6-fluorobenzonitrile(CAS: 94088-45-6)

CAS Number
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Basic Information
Molecular Formula
C14H10FNO
Molecular Weight
17.03 g/mol
Physical Properties
Density
1.21±0.1 g/cm3 (20 ºC 760 Torr),
Chemical Identifiers
SMILES
C1=CC=C(C=C1)COC2=C(C(=CC=C2)F)C#N
InChIKey
ITKHCBLEEGSDOF-UHFFFAOYSA-N
Database References
MDL Number
MFCD00068211
FAQ
2-(Benzyloxy)-6-fluorobenzonitrile (CAS: 94088-45-6) is a crystalline solid with a molecular weight of approximately 227.18 g/mol. It has a low solubility in water but is more soluble in organic solvents such as methanol and ethanol. Chemically, it is reactive and can undergo nucleophilic substitution reactions. It does not readily decompose under normal conditions but should be stored in a cool, dry place to prevent potential hydrolysis.
2-(Benzyloxy)-6-fluorobenzonitrile (CAS: 94088-45-6) is typically synthesized via a multistep process involving the use of fluorine-containing reagents and benzyl alcohol. The reaction involves the nucleophilic substitution of a fluorine atom onto a benzene ring followed by the introduction of a benzyloxy group. Commonly, this is achieved using potassium fluoride and benzyl alcohol in the presence of a catalyst such as a Lewis acid or a base. The reaction is highly selective and provides good yields.
2-(Benzyloxy)-6-fluorobenzonitrile (CAS: 94088-45-6) is used in various industries, particularly in pharmaceuticals where it serves as a key intermediate in the synthesis of complex molecules. It is also utilized in the production of certain polymers for electronic applications, as a sensor component, and in semiconductor manufacturing processes where its unique chemical properties are leveraged.
What precautions should be taken when handling 2-(Benzyloxy)-6-fluorobenzonitrile (CAS: 94088-45-6)?
When handling 2-(Benzyloxy)-6-fluorobenzonitrile (CAS: 94088-45-6), it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. The compound should be stored in a fume hood to prevent inhalation. In case of spill, it should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information. Handling should be conducted in a well-ventilated area to minimize exposure risk.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
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