5-Amino-1-(2-methyl-2-propanyl)-1H-pyrrole-3-carbonitrile(CAS: 269726-49-0)

5-Amino-1-(2-methyl-2-propanyl)-1H-pyrrole-3-carbonitrile (CAS: 269726-49-0) is a solid with a crystalline form. Its molecular weight is approximately 160.21 g/mol. The compound is slightly soluble in water. It is chemically stable under normal conditions but can react with strong acids and bases. It is not flammable but may decompose at high temperatures, releasing toxic gases.

5-Amino-1-(2-methyl-2-propanyl)-1H-pyrrole-3-carbonitrile is typically synthesized via a multi-step process involving the reaction of 2-methyl-2-propanamine with 3-nitropyridine followed by reduction and amidation. Common catalysts include palladium-based catalysts. The overall yield is around 70-80%, with high selectivity towards the desired product.

5-Amino-1-(2-methyl-2-propanyl)-1H-pyrrole-3-carbonitrile finds applications in the pharmaceutical industry for the synthesis of drug intermediates. It is also used in the development of sensors and semiconductors. The compound's unique chemical structure makes it valuable for its reactivity and stability in various applications.

When handling 5-Amino-1-(2-methyl-2-propanyl)-1H-pyrrole-3-carbonitrile (CAS: 269726-49-0), it is essential to wear personal protective equipment (PPE) such as gloves, safety goggles, and lab coats. Work in a well-ventilated area or fume hood to avoid inhalation. Spills should be contained and cleaned up using appropriate absorbents. Ensure to follow the safety data sheet (SDS) for detailed handling procedures and emergency responses.