(9E,12E,15E)-9,12,15-Octadecatrienoic acid(CAS: 68132-21-8)

(9E,12E,15E)-9,12,15-Octadecatrienoic acid is a solid crystalline compound with a molecular weight of approximately 278.43 g/mol. It has a low solubility in water (less than 1 g/L) but is more soluble in organic solvents such as ethanol and chloroform. This acid exhibits typical reactivity for carboxylic acids, including esterification and transesterification reactions.

(9E,12E,15E)-9,12,15-Octadecatrienoic acid can be synthesized through the hydrolysis of 9,12,15-octadecatrienoyl chloride, an intermediate obtained from the dehydration of 9,12,15-octadecatrienoic anhydride. Alternatively, it can be produced via direct hydrogenation of 9,12,15-octadecatrienal, a process that provides good yield and selectivity for the desired cis configuration.

(9E,12E,15E)-9,12,15-Octadecatrienoic acid finds applications in various industries. Its use in the pharmaceutical sector includes as a precursor for drug synthesis. In the polymer industry, it serves as an additive for enhancing the mechanical properties of polymers. Additionally, it is utilized in the manufacturing of sensors and as a component in semiconductors for its unique electronic properties.

When handling (9E,12E,15E)-9,12,15-Octadecatrienoic acid, wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Ensure the use of a fume hood to minimize inhalation risks. Store the compound in a cool, dry place away from heat and light sources. In case of spill, use appropriate absorbents and dispose of them according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.