Andrographidine C(CAS: 113963-39-6)

Andrographidine C is a white crystalline powder with a molecular weight of approximately 346.34 g/mol. It is sparingly soluble in water and ethanol. This compound is relatively stable under normal conditions but reacts with strong acids to form salts. It is insoluble in common organic solvents such as chloroform and acetone. Its reactivity is moderate, and it should be handled with care to avoid decomposition.

Andrographidine C can be synthesized through a multistep process involving the condensation of andrographolide with an appropriate nucleophile. Common methods include the use of thymol as a starting material, followed by Wittig reactions and subsequent hydrogenation. The overall yield is moderate, and the process requires careful control of temperature and pH to achieve high selectivity.

Andrographidine C finds applications in the pharmaceutical industry, particularly in the development of anti-inflammatory and antiviral drugs. It is also used in the production of natural health products and dietary supplements. Additionally, it has potential uses in the cosmetic industry and as a flavor enhancer in food products.

Handling Andrographidine C requires the use of personal protective equipment (PPE) such as gloves, safety goggles, and lab coats. It should be stored in airtight containers in a cool, dry place away from direct sunlight. In case of spills, it is recommended to use a fume hood and follow standard laboratory safety procedures. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.