(3alpha,5beta,7alpha,12alpha)-3,7,12-Trihydroxy(2,2,4,4-~2~H_4_)cholan-24-oic acid(CAS: 116380-66-6)

The compound (3alpha,5beta,7alpha,12alpha)-3,7,12-Trihydroxy(2,2,4,4-~2~H_4_)cholan-24-oic acid is a crystalline solid with a molecular weight of approximately 424.52 g/mol. It is slightly soluble in water and organic solvents. The compound is reactive with strong acids and bases, and it can undergo hydrolysis under alkaline conditions.

This compound is typically synthesized via a multi-step process involving saponification of cholesterol, followed by enzymatic or chemical transformations. Common catalysts include alkaline earth metal hydroxides and organometallic compounds. The synthesis yields a high purity product with good selectivity and acceptable yield.

This compound is used in the pharmaceutical industry for producing bile acid analogs, which are important in the treatment of cholesterol-related disorders. It is also utilized in the polymer industry for synthesizing biodegradable polymers and in the semiconductor industry for developing chemical vapor deposition precursors.

When handling this compound, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. It should be stored in a cool, dry place away from direct sunlight and heat sources. Fume hood use is recommended during handling. In case of spill, it should be cleaned up carefully according to safety data sheet (SDS) guidelines.