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1-Ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid - nicotinic acid (1:1)(CAS: 118803-81-9)

1-Ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid - nicotinic acid (1:1)
CAS Number

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Basic Information

Molecular Formula
C22H23FN4O5
Molecular Weight
442.45 g/mol

Physical Properties

Melting Point
277-280 °C(lit.)
Boiling Point
555.8°C at 760 mmHg
Flash Point
289.9 °C

Chemical Identifiers

SMILES
CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O.C1=CC(=CN=C1)C(=O)O
InChIKey
WRIFLTAYLRDENF-UHFFFAOYSA-N

Database References

MDL Number
MFCD00873666

FAQ

This compound has a crystalline form and a molecular weight of approximately 501.78 g/mol. It is slightly soluble in water and ethanol. Chemically, it is reactive towards bases and can undergo hydrolysis under basic conditions. It is also known for its stability under acidic conditions.
This compound is typically synthesized by the condensation of 1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid with nicotinic acid. The reaction is catalyzed by a suitable base and proceeds with good selectivity and yield, typically around 80-90%. The exact conditions depend on the purity of starting materials and reaction temperature.
This compound is primarily used in the pharmaceutical industry as an intermediate for the synthesis of other drugs. It can also find applications in the development of sensors and semiconductors due to its unique chemical properties.
When handling this compound, it is recommended to use appropriate personal protective equipment (PPE) such as gloves and safety goggles. The compound should be stored in a fume hood to minimize exposure. Spills should be handled carefully, and the site should be decontaminated using appropriate solvents. Always refer to the safety data sheet (SDS) for detailed handling and storage information.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

Contact Information

Email

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