Compound Q&A
How is 1-Ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid - nicotinic acid (1:1) (CAS: 118803-81-9) typically synthesized?
Answer
This compound is typically synthesized by the condensation of 1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid with nicotinic acid. The reaction is catalyzed by a suitable base and proceeds with good selectivity and yield, typically around 80-90%. The exact conditions depend on the purity of starting materials and reaction temperature.
About
CAS No
118803-81-9
English Name
1-Ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid - nicotinic acid (1:1)
Molecular Formula
C22H23FN4O5
Molecular Weight
442.44700000000023 g/mol
SMILES
CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O.C1=CC(=CN=C1)C(=O)O
InChIKey
WRIFLTAYLRDENF-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:18