Glycyl-L-proline(CAS: 704-15-4)

Glycyl-L-proline (CAS: 704-15-4) is a crystalline compound with a molecular weight of approximately 187.23 g/mol. It is slightly soluble in water and has a pKa of 2.7. This compound exhibits moderate reactivity, particularly in amide bond formation. It is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

Glycyl-L-proline (CAS: 704-15-4) can be synthesized via the coupling of glycine and L-proline. Commonly, this is achieved using chemical coupling reagents such as 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) and N-hydroxysuccinimide (NHS). The yield can reach up to 75%, with high selectivity for the desired product.

Glycyl-L-proline (CAS: 704-15-4) is used in various industries. In pharmaceuticals, it serves as a building block for peptide synthesis. It is also utilized in the production of polymers, where it acts as a monomer. Additionally, it finds applications in sensors and semiconductors due to its unique chemical properties.

When handling Glycyl-L-proline (CAS: 704-15-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood. In case of spillage, avoid contact with skin and eyes, and clean up using appropriate chemical spill kits. Always consult the Safety Data Sheet (SDS) for detailed handling instructions.