(6-(2-Hydroxypropan-2-yl)pyridin-3-yl)boronic acid(CAS: 1088496-42-7)

(6-(2-Hydroxypropan-2-yl)pyridin-3-yl)boronic acid is a crystalline solid with a molecular weight of approximately 279.25 g/mol. It has a solubility of about 0.001 g/100 mL in water. This compound is known for its reactivity in boron-containing reactions and its ability to act as a boronic acid derivative, which is common in Suzuki coupling reactions. It is also stable under normal laboratory conditions but may react with strong acids or bases.

(6-(2-Hydroxypropan-2-yl)pyridin-3-yl)boronic acid can be synthesized using a multi-step process starting from 2-hydroxypropyl pyridine and boronic acid. The synthesis involves protecting the hydroxyl group, followed by a reaction with boronic acid in the presence of a palladium catalyst and a base. The yield is typically around 70-80%, with high selectivity for the desired product.

(6-(2-Hydroxypropan-2-yl)pyridin-3-yl)boronic acid is primarily used in the pharmaceutical and polymer industries. It serves as a key intermediate in the synthesis of various drugs and also finds applications in the development of functional polymers. Additionally, it is used in the field of sensors for its unique boronic acid functionality.

When handling (6-(2-Hydroxypropan-2-yl)pyridin-3-yl)boronic acid, it is important to wear appropriate personal protective equipment (PPE), including gloves and goggles. It should be stored in a cool, dry place, away from strong acids and bases. In case of a spill, it should be cleaned up immediately using appropriate absorbent materials. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.