Ethyl 1-(4-bromophenyl)cyclopropanecarboxylate(CAS: 1215205-50-7)

Ethyl 1-(4-bromophenyl)cyclopropanecarboxylate is a colorless to light yellowish liquid with a molecular weight of approximately 299.04 g/mol. It has a low solubility in water (less than 1 g/100 mL) and is more soluble in organic solvents such as ethanol and acetone. The compound is moderately reactive, particularly towards nucleophiles, and is used in synthesis reactions. It crystallizes at around -75°C and has a boiling point of 175°C. It is stable under normal conditions but should be handled with care to avoid decomposition under strong basic conditions.

Ethyl 1-(4-bromophenyl)cyclopropanecarboxylate can be synthesized via the reaction of 4-bromophenyl cyclopropanecarboxylic acid with ethyl bromide in the presence of a base such as sodium hydride. The yield is typically around 75%, and the reaction is carried out at room temperature with good selectivity. The reaction is monitored by TLC or GC (gas chromatography) to ensure the product formation.

Ethyl 1-(4-bromophenyl)cyclopropanecarboxylate is used in the pharmaceutical industry for the synthesis of certain drugs. It is also used in the polymer industry for the development of advanced polymer materials. Additionally, it is employed in the semiconductor industry for the fabrication of electronic devices, and in the sensor industry for the development of gas sensors. Its unique chemical structure makes it a valuable reagent in these sectors.

When handling Ethyl 1-(4-bromophenyl)cyclopropanecarboxylate, appropriate Personal Protective Equipment (PPE) should be worn, including gloves, safety goggles, and lab coat. The compound should be handled in a well-ventilated area or a fume hood. Spills should be carefully cleaned up using appropriate absorbents, and the area should be thoroughly rinsed. In case of contact with eyes or skin, immediate rinsing with copious amounts of water is recommended. The Safety Data Sheet (SDS) should be consulted for detailed emergency handling procedures.