3-Methyl-2-butanone(CAS: 563-80-4)

3-Methyl-2-butanone (CAS: 563-80-4) is a colorless, slightly sweet-smelling liquid with a molecular weight of 98.13 g/mol. It has a boiling point of 79.3°C and a melting point of -88°C. The compound is moderately soluble in water but is highly soluble in organic solvents. Chemically, it is reactive and can undergo dehydration, oxidation, and alkyl halide formation reactions.

3-Methyl-2-butanone (CAS: 563-80-4) is commonly synthesized via the dehydration of 3-methyl-2-butanol using concentrated sulfuric acid as a catalyst. The reaction is exothermic and typically yields 90-95% of the product. Other methods include the reaction of methyl acetate with propionaldehyde or the oxidation of 2-methyl-1-butanol.

3-Methyl-2-butanone (CAS: 563-80-4) is widely used in various industries. It serves as a raw material in the production of pharmaceuticals, particularly as a precursor for ibuprofen. It is also used in the manufacturing of polymers, as an intermediate in the synthesis of fragrances, and in the production of certain chemical sensors and semiconductors.

When handling 3-Methyl-2-butanone (CAS: 563-80-4), it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. The compound should be stored in a well-ventilated area and used in a fume hood to minimize inhalation risk. In case of a spill, the area should be ventilated and the spill cleaned up using absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.