2-{4-[(R)-(4-Chlorophenyl)(phe(CAS: 705289-61-8)

2-{4-[(R)-(4-Chlorophenyl)phenyl]amino}benzoic acid, also known as Cilengitide, is a small molecule compound with a molecular formula of C22H17ClNO4. It is a potent integrin αvβ3 inhibitor used in research for its potential in treating certain types of cancer, particularly glioblastoma multiforme and other solid tumors.

2-{4-[(R)-(4-Chlorophenyl)phenyl]amino}benzoic acid is primarily used in pharmaceutical research for its inhibitory activity against integrin αvβ3, a receptor involved in tumor angiogenesis and metastasis. It is also studied for potential therapeutic applications in cancer treatment.

While 2-{4-[(R)-(4-Chlorophenyl)phenyl]amino}benzoic acid is considered safe under controlled laboratory conditions, it should be handled with caution as it is a potent compound. It is important to follow standard safety protocols, including wearing appropriate personal protective equipment (PPE) and storing it in a secure, well-ventilated area to prevent exposure and inhalation risks.

2-{4-[(R)-(4-Chlorophenyl)phenyl]amino}benzoic acid should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent moisture and light exposure. Additionally, it is crucial to store it under lock and key to ensure it is inaccessible to unauthorized personnel.